Saturday 14 November 2020

Top 9 Antibiotics and their IUPAC Names

 The top 9 Antibiotics and their IUPAC Names are:

  • Amoxicillen;
(2S,5R,6R)-6-[[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid.

  • Doxycycline;
[4S(4aR,5S,5aR,6R,12aS)]-4-(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11deoxonaphthacene-2-carboxamide monohydrochloride, compound with ethyl alcohol (2:1), monohydrate.
  • Cephalexin;
(6R,7R)-7-[[(2R)-2-amino-2-phenylacetyl]amino]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.

  • Ciprofloxacin;
1-cyclopropyl-6-fluoro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid.

  • Clindamycin;
Methyl 7-chloro-6,7,8-trideoxy-6ร‚(1-methyl-trans-4-propyl-L-2-pyrrolidinecarboxamido)-1-thio-L-threo-ฮฑ-D-galactoร‚octopyranoside monohydrochloride.

  • Metronidazole;
2-(2-methyl-5-nitroimidazol-1-yl)ethanol;hydrochloride.

  • Azithromycin;
(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-11-[(2S,3R,4S,6R)-4-(dimethylamino)-3-hydroxy-6-methyloxan-2-yl]oxy-2-ethyl-3,4,10-trihydroxy-13-[(2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyloxan-2-yl]oxy-3,5,6,8,10,12,14-heptamethyl-1-oxa-6-azacyclopentadecan-15-one.

  • Sulfamethoxazole;
4-amino-N-(5-methyl-1,2-oxazol-3-yl)benzenesulfonamide;5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine.

  • Trimethoprim;
5-[(3,4,5-trimethoxyphenyl)methyl]pyrimidine-2,4-diamine.

Sunday 5 July 2020

What about yellow fever?


Yellow fever is a hemorrhagic condition that may lead to a high fever, bleeding into the skin, and cell death in the kidney and liver. 
                                       
                                                    
                                  Yellow fever is a viral infection spread by a certain type of mosquito that is the yellow fever mosquito Aedes aegypti and this viral disease is typically short duration. This viral infection spread by a particular type of mosquito. This infection is most common in areas of South America and Africa since 1980s, and also the number of cases of yellow fever has been increasing. 


The main cause of yellow fever is Virus and Vector is Female Aedes Aegypti. The female Aedes must bite a diseased person within first 4 days of the disease. After 10 to 20 days of latent period, the Aedes becomes infective, as long as 7 months.  Incubation period of yellow fever is - 3 to 6 days.